News Snapshot:
A NEW study led by Chinese university scientists has identified a compound derived from the antiviral drug remdesivir that exhibits potential as an oral treatment for COVID-19. Published in the journal Science Translational Medicine, the study shows that ATV006, which was synthesized from the remdesivir derivative GS-441524, demonstrated improved oral absorption and robust antiviral efficacy against SARS-CoV-2 and variants in animal tests. According to previous studies, GS-441524, though effective against SARS-CoV-2, suffers from poor oral bioavailability, which hampers its further development as an oral drug. In the study, scientists from Sun Yat-sen University and Shenzhen-based Southern University of Science and...